blood viscosity can be reduced by
Thus, blood plays an extremely important role in the life and health of the body. Most subjects came to the research premises with no pain (Table 2). McHedlishvili G, Maeda N . A 2008 study was the first to report on the zeta potential of red blood cells in patients with diabetes.6 Researchers from the University of Calcutta described a remarkable alteration in the electrodynamics of RBCsa progressive deterioration of the zeta potential and hypercoagulability among patients with diabetes, which was even worse among those who also had CVD. Foods high in cholesterol and unsaturated fatty acids, Child with Mouth Ulcers and Bleeding Gums: Causes and Remedies, Exercise Guide for Individuals with Spinal Degeneration. The relationship between blood viscosity and blood pressure in a random sample of the population aged 55 to 74 years. How to reduce blood viscosity? Cell Aggregate Results for the 10 Subjects. The McGill Pain Questionnaire (MPQ) was used to evaluate the level and location of pain before and after grounding sessions.23, Pain, Medication and Health Condition of Each Subject. Hyperviscosity syndrome is a condition that makes it impossible for blood to flow freely through the arteries. Subsequently, 24h urine was collected for measurements of creatinine clearance and urinary albumin excretion. Particle electrophoresis as a tool to understand the aggregation behavior of red blood cells. Nikolov KV. Small changes in viscosity produce large differences in total resistance,13 especially in peripheral vessels <30m in diameter, in which the relative effective viscosity can increase six- to sevenfold.14 These results confirm the existence of a blood hyperviscosity syndrome in hypertension. It should be combined with other tests to decide on the diagnosis and have an appropriate treatment plan. Keltner JR, Roos MS, Brakeman PR, Budinger TF. The gold bars were connected to two 9-volt batteries in series. If any Dispute cannot be resolved informally, you agree that any and all Disputes, including the validity of this arbitration clause and class action waiver, shall be submitted to final and binding arbitration before a single arbitrator of the American Arbitration Association (AAA) in a location convenient to you or telephonically. Stress: Thief in the night. In addition, such viscosity reduction does not affect the red blood cells' normal function. Although limited for these reasons, the results of this study indicate that increased blood viscosity is a risk for renal damage before the development of kidney disease in EHT. Blood proteins are in plasma in colloidal state. Essential hypertension is an important cause of end-stage renal disease. Some patients with anemia have low hematocrits, and therefore reduced blood viscosities. The disease can also occur when red blood cells have an abnormal shape, such as sickle cell anemia. Patients were instructed not to take food, alcohol, caffeine or smoke within 12h before blood samplings, although water ingestion was not restricted. Phys Med Biol. Interestingly, the subject with the largest increase in zeta potential after 2 hours of grounding, with a factor of 5.63 (subject #6), did not have pain upon arriving at the clinic to be tested. Doncheva NI. Ruggenenti P, Remuzzi G . 2004 Jul 21;49(14):3267-77. doi: 10.1088/0031-9155/49/14/017. The goal was to find if grounding affects RBC zeta potential and RBC aggregation in an ordinary office environment. Chevalier G. Mori K. Oschman JL. In adults, this syndrome can also be seen with autoimmune diseases such as rheumatoid arthritis or lupus erythematosus. In the morning, venous blood was collected in tubes containing potassium EDTA for determination of blood and plasma viscosity after a 30-min supine rest at the outpatient clinic. Currently, the only method of treatment is to take drugs such as aspirin, which has, however, several unwanted side effects. The process is repeatable. This preventive miracle can be attributed to the most overlooked factor in heart health: blood viscosity. The viscosity of blood will increase when the body loses water due to diarrhea, loss of sweat when working or a sudden cold, etc. Your consent is not required to purchase goods or services. The subject was then asked to sit in a comfortable reclining chair in the soundproof experiment room with the lights dimmed or off, depending on the subject's level of comfort with darkness. Besarab A, Bolton WK, Browne JK, Egrie JC, Nissenson AR, Okamoto DM, Schwab SJ, Goodkin DA . Or difficult to distinguish from cases of increased blood viscosity or other temporary causes. Huikuri HV. Brimble KS, McFarlane A, Winegard N, Crowther M, Churchill DN . Here we report our new finding that the blood viscosity can be reduced by pulsed magnetic field. 8600 Rockville Pike Where in the body are worn-out and damaged red blood cells destroyed? Explain how pressure drops due to resistance. MeSH This puts the patient at risk for the consequences of thromboembolic events. Want daily emails from Dr. Inglis delivered to your inbox every day? Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. Careers, Unable to load your collection due to an error. Because there were 10 subjects, each value presented in Table 4 for cluster sizes 1, 2, and 3, is the average of 120 cell-cluster counts for each size before and 120 after 2 hours of earthing. Letcher RL. In: Lanzerotti LJ, editor. Article Hormones present in plasma will participate in chemical processes in the body, regulating the activities of organs. If your baby is unusually sleepy or doesnt want to feed, this is a sign that something is wrong. It seems that the healthier a subject was, the less significant the increase was (see Table 2 for subjects' health conditions). Epub 2019 Mar 15. The average zeta potentials before and after 2 hours of grounding for the 7 subjects with no pain were 7.85 before grounding and 20.45 after grounding, respectively (an average increase by a factor of 2.61), which shows less of an improvement. Blood is a complex fluid containing a variety of formed elements (cells), proteins, nutrients, and metabolic waste products, along with dozens of clotting factors. Grow Power Review: Is It Really Effective. Please read these terms carefully. Hypertension, blood viscosity, and capillary spasm. Unauthorized use of these marks is strictly prohibited. WebCardiac pump failure, hypovolemia, and increased blood viscosity all reduce cerebral blood flow. The electrode system consisted of 2 gold bars (2.0mm2.0mm square cross-section and 5.0cm in length) placed directly on the microscope slide at the sides of the cover slip (Fig. Emerging research is revealing that direct physical contact of the human body with the surface of the earth (grounding or earthing) has intriguing effects on human physiology and health, including beneficial effects on various cardiovascular risk factors. The severity of the disease depends on the cause. Dittrich S, Kurschat K, Lange PE . One magnetic field pulse of 1.3 T lasting ~1 min can reduce the blood viscosity by 20%-30%. Clin Hemorheol 1993; 13: 651659. Without unsaturated fatty acids. The electric field was calculated from the electric potential and the distance between electrodes. 8600 Rockville Pike Chevalier G. Mori K. The effect of earthing on human physiology: Part 2. Applewhite R. Effectiveness of a conductive patch and a conductive bed pad in reducing induced human body voltage via the application of earth ground. Similarly, electric charges of the same sign repel each other when they are in proximity to one another. Thus, increased blood viscosity is considered as one of the important cardiovascular risk factors in the advanced stage as well as early stage of essential hypertension. Anyone you share the following link with will be able to read this content: Sorry, a shareable link is not currently available for this article. And youre never going to believe just how dramatically blood donation can slash heart attack risk. Int J Biomed Sci. A higher repulsive surface charge increases spacing between erythrocytes, reduces clumping, lowers viscosity, and lowers peripheral resistance to flow.9 Conditions that reduce RBC surface charge correlate with occlusive arterial disease because of a higher incidence of RBC aggregation.5 It is accepted that blood viscosity and resistance to blood flow are related and are elevated in patients who have hypertension.1012 Total resistance is the product of vascular resistance and viscosity. CAS Explain what viscosity is. Exclusion criteria were: (1) pregnancy; (2) age <18 or >80; (3) taking pain, anti-inflammatory medications, sedatives, or prescription sleeping medications (<5 days prior to testing); (4) taking psychotropic drugs or diagnosis with a mental disorder; (5) recent surgery (<1 year); (6) documented life-threatening disease (such as cancer, AIDS, etc. What does the Rh factor do? There was clearly less clumping after 2 hours of grounding than before grounding. When physicians recommend evidence-based, harmless, and simple natural interventions, alleviation of human suffering and improved quality of life can be realized. In particular, the main functions can be mentioned as protecting the body, regulating body temperature, supporting excretion, providing nutrition, etc. Standard microscope slides (75mm25mm, 1-mm thick) and cover slips (20mm20mm, or 22mm22mm, 0.2-mm thick) were used. Given that there were 2 blood draws before earthing and 2 after earthing, 12 counts were done for each cluster size per subject before earthing and 12 counts were done after 2 hours of earthing. 1980;42:311-24. doi: 10.1146/annurev.ph.42.030180.001523. As the heart contracts, mechanical energy is transferred from the heart to the blood; a small part of the energy is dissipated by the viscosity of the You may contact us by telephone at 1-800-494-5726 orhelp@nutritionandhealing.com. Especially, alpha-1 blockers could be recommended because they reduce not only blood viscosity but also albuminuria in EHT.38, 39 Third, our data did not support the notion that increased urinary albumin excretion could reflect systemic endothelial dysfunction in EHT.40 Because the endothelial function was estimated only by plasma NOx in our study, the measurements of other substances released from endothelial cells, such as prostacyclin, or blood flow during reactive hyperemia should have been performed for the precise evaluation of endothelial functions.41, 42 Fourth, in the present study, the value of creatinine clearance seemed to be relatively high according to their age, possibly due to increase in the tubular secretion of creatinine into urine.43 The accurate and reliable method such as inulin clearance should have been employed for the measurement of glomerular filtration rate. Microalbuminuria in hypertension. Nephrol Dial Transplant 1999; 14: 22712278. To the fullest extent permitted by applicable law, no arbitration under this Agreement may be joined to an arbitration involving any other party subject to this Agreement, whether through a class action, private attorney general proceeding, class arbitration proceedings or otherwise. The researchers also indicated that high blood sugar levels are associated with significant alterations in the electrodynamics of an RBC's outer membrane and may increase the potential for RBC clumping. Should Individuals with Spondylosis Take Calcium? Flow effects on prostacyclin production by cultured human endothelial cells. Accessibility Text Messaging and Telemarketing Terms and Conditions. Vink H. Wieringa PA. Spaan JAE. Increased blood viscosity can occur in both children and adults. Among them were age, body mass index (BMI), mean blood pressure (that is, diastolic blood pressure plus pulse pressure/3), pulse rate, triglyceride, HDL cholesterol, HOMA-IR and serum high-sensitive C-reactive protein.24, 25, 26, 27 A P-value less than 0.05 was considered statistically significant. Urinary albumin concentration was determined using immunoturbidimetry. The t-test method could also provide useful information for investigators planning future research projects with a larger number of subjects. Chevalier G. Sinatra ST. Statistical Principles in Experimental Design. The objectives of therapy are to optimize hematocrit (Figure 2), improve RBC deformability, decrease plasma viscosity, reduce RBC aggregation, and normalize body Sinatra, and J.L. The results show that grounding the body to soil increases the zeta potential and thereby decreases aggregation of RBCs. The red cell electrophoretic mobility in atherosclerotic and other individuals. Reduced renal function and/or elevated albuminuria reflect wide-spread cardiovascular damages as well as glomerular impairment, indicating an increased risk of future cardiovascular and renal disease.32, 33, 34, 35 In the present study, increased blood viscosity was associated with reduced renal function and increased urinary albumin excretion in EHT without renal disease, although the hemorheological variables were not different between EHT and normotensive subjects. Consequently, grounding leads to rapid equalization of the electrical potential of the body with the potential of the Earth (planet) through an almost instantaneous transfer of electrons from soil to the body.18,19 This has been the natural bioelectrical environment of the human body and of other organisms throughout most of evolutionary history. How to reduce blood viscosity? Similar patches and wires from the hands were also connected to the box to ground the hands. Google Scholar. A number of clinical studies on the physiologic effects of grounding the human body have indicated improvements in various cardiovascular and heart-related parameters. The other subject reported that her pain had nearly vanished by the end of the session. Am J Cardiol 1984; 54: 592595. Aggregation proteins that will be able to bind red blood cells together to form erythrocytes are fibrinogen, globulins, lipoprotein very low density and circulating immune complexes. Measuring electrical and mechanical properties of red blood cells with double optical tweezers. Bronte-Stewart B. Zannad F. Voisin P. Brunotte F, et al. HOWEVER, YOU UNDERSTAND AND AGREE TO HAVE ANY CLAIMS DECIDED INDIVIDUALLY AND ONLY THROUGH ARBITRATION. This technology has much potential for physical therapy. Creatinine clearance and urinary albumin excretion were 12333 (60208)mlmin1 per 1.73m2 and 1919 (1106)mg per day, respectively. [Mar 29;2008 ]. Informed consent was obtained from all subjects prior to their participation. Federal government websites often end in .gov or .mil. Wires from a standard electrostatic discharge ground system were snap-attached to the patches and connected to a box (Fig. Dynamics of glomerular ultrafiltration in the rat. The findings in this pilot study indicate that grounding has a safe and significant effect on zeta potential and that further study is warranted. There was no difference in blood viscosity and plasma viscosity between 23 EHT (4.240.41mPaS, 1.730.08mPaS) and the same number of age- and sex-matched normotensive subjects (4.250.42mPaS, 1.720.07mPaS). The combined effect of magnetic and electric fields using on/off infrared light on the blood sugar level and the diameter of Langerhans islets of diabetic mice. official website and that any information you provide is encrypted Article The electrophoretic mobility or zeta potential can be measured by determining the mobility of RBCs in an imposed electric field. Fiber also plays a role in hindering the absorption of nutrients such as glucose, cholesterol, lipids, reducing blood cholesterol, .. Hypertension: Pathophysiology, Diagnosis, and Management, 2nd edn, pp 365376 (Raven Press: New York, 1995). Notwithstanding the foregoing, the following shall not be subject to arbitration and may be adjudicated only in the state and federal courts of Maryland: (i) any dispute, controversy, or claim relating to or contesting the validity of our or one of our family companys intellectual property rights and proprietary rights, including without limitation, patents, trademarks, service marks, copyrights, or trade secrets; (ii) an action by us for temporary or preliminary injunctive relief, whether prohibitive or mandatory, or other provisional relief; (iii) any legal action by us against a non-consumer; or (iv) interactions with governmental and regulatory authorities. Blood viscosity, but not plasma viscosity, correlated negatively with creatinine clearance. Velcheva I, Antonova N, Titianova E, Damianov P, Dimitrov N, Dimitrova V . For hemorheological measurements, whole blood viscosity and plasma viscosity were determined using a falling ball microviscometer (AMVn-200, Anton Paar, Austria).21 This instrument comprises a glass capillary tube of 0.16mm internal diameter, containing a metallic ball of 0.15mm diameter. In contrast, in the diagnostic evaluation of thrombotic diseases, blood viscosity testing will often be ordered. Who is at risk for hyperviscosity syndrome? Gessner T, et al. In adults, hyperviscosity syndrome typically causes symptoms when blood viscosity is between 6 and 7, measured relative to saline, but it can be lower. Jeong SK, Cho YI, Duey M, Rosenson RS . Table 1 details age and gender distribution of subjects; Table 2 documents their pain levels before and after each session, as well as medications and general health condition of each subject. The thicker and stickier the blood, the more abrasion and damage it does to the cells lining (endothelium) the arteries. ARBITRATION IS MANDATORY AND THE EXCLUSIVE REMEDY FOR ANY AND ALL DISPUTES RELATED TO THIS WEBSITE, THIS AGREEMENT, AND ANY TELEPHONE CALLS, EMAILS, OR TEXT MESSAGES THAT YOU RECEIVE FROM OR ON BEHALF OF US, UNLESS SPECIFIED BELOW OR UNLESS YOU OPT-OUT. Similarly, blood viscosity is known to increase in a number of clinical situations, such as hypertension, smoking, lipid disorders, advancing age, and diabetes mellitus. Stay informed and motivated as you embark on your journey towards a balanced and vibrant life. Effect of chronic kidney disease on red blood cell rheology. Wade IM. Therefore, the viscosity of blood in each person is different. When blood viscosity increases, it damages blood vessels and increases the risk of heart attacks. New trends in clinical hemorheology: an introduction to the concept of the hemorheological profile. Anxiety Disorders, Stress When Should You Take Medicine? Go AS, Chertow GM, Fan D, McCulloch CE, Hsu CY . Sugimori H, Tomoda F, Koike T, Kinuno H, Kurosaki H, Masutani T, Inoue H . No action should be taken based solely on the contents of this site. Aggregation proteins that will be able to bind red blood cells together to form erythrocytes are fibrinogen, globulins. Dispute Resolution by Binding Arbitration and Class Action Waiver. 2). Pursuant to any applicable statutes, regulations, rules, ordinances or other laws, including without limitation the United States Electronic Signatures in Global and National Commerce Act, P.L. You are not required to agree to this as a condition of making a purchase. Accessibility Call 1-800-494-5726 to learn more. Toth K, Kesmarky G, Vekasi J, Nemes J, Czopf L, Kapronczay P, Halmosi R, Papp E, Juricskay I . In short number of blood platelets reduces blood viscosity. Am J Physiol 1972; 223: 11841190. The Impact of Biophysical Properties of Erythrocytes on their Aggregation. Blood viscosity is a direct measure of the bloods resistance to flow. ISSN 0916-9636 (print), Increased blood viscosity is associated with reduced renal function and elevated urinary albumin excretion in essential hypertensives without chronic kidney disease, A tip-coupled, two-cantilever, non-resonant microsystem for direct measurement of liquid viscosity, Transient Fanconi Syndrome in a Child with Acute COVID-19 Infection: Authors Reply, Phenotypic diversity and metabolic specialization of renal endothelial cells, In vitro investigation of the impact of pulsatile blood flow on the vascular architecture of decellularized porcine kidneys, Time-resolved fluorescence determination of albumin using ZnGeO:Mn luminescence nanorods modified with polydopamine nanoparticles.
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